Download Animal, Plant, and Microbial Toxins: Volume 2 Chemistry, by Nobuyo Maeda, Nobuo Tamiya, Y. M. Chen, C. Y. Lee (auth.), PDF

By Nobuyo Maeda, Nobuo Tamiya, Y. M. Chen, C. Y. Lee (auth.), Akira Ohsaka, Kyozo Hayashi, Yoshio Sawai, Ryosuke Murata, Masaru Funatsu, Nobuo Tamiya (eds.)

During the earlier twenty years, learn on animal, plant, and microbial pollution has improved quickly, and new and interesting info has looked as if it would make clear either the medical and healing points of intoxication and, much more impor­ tant, to aid us comprehend extra precisely the constitution and the mode of motion of poisons on a molecular foundation. end result of the interdisciplinary nature of toxin learn, it's of significant impor­ tance that employees focusing on its assorted elements should still make a selected attempt to replace and stay alongside of new advancements during this rapidly-expanding box. This has been one of many major reasons of the sequence of overseas conferences which were held during the last ten years. The expanding curiosity within the result of toxin learn should be defined partially by means of the turning out to be normal preoccupation with pollutants and its poisonous results, which means extra anq extra experts in different fields are discovering it essential to keep up a correspondence with present examine into clearly taking place pollution. The papers in those volumes have been provided on the Fourth overseas Symposium on Animal, Plant and Microbial pollutants, geared up by means of the Inter­ nationwide Society on Toxicology, held in Tokyo in September, 1974. The editors have made up our minds to incorporate either unique studies and evaluate articles, prepared in response to disciplines. modifying has been saved to the minimal helpful for enough comprehension of the materials.

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Additional resources for Animal, Plant, and Microbial Toxins: Volume 2 Chemistry, Pharmacology, and Immunology

Example text

Lee, C. , Chang, C. , Chiu, T. , Chiu, P. J. , Tseng, T. , and Lee, S. Y. (1968). Pharmacological properties of cardiotoxin isolated from Formosan cobra venom, Arch. Exp. Pathol. Pharmacol. 259: 360-374. Lee, C. , Chang, C. , and Chen, Y. M. (1972). Reversibility of neuromuscular blockade by neurotoxins from Elapid and sea snake venoms, J. Formosan Med. Assoc. 71: 344349. , and Tamiya, N. (1974). The primary structure of the toxin Laticauda semifasciata III, a weak and reversibly acting neurotoxin from the venom of a sea snake, Laticauda semifasciata, Biochem.

Residue 23 appeared to be methionine. Digestion of the reduced and S-carboxymethylated notexin with carboxypeptidase A liberated one residue of glutamine from the carboxyl terminus. Peptide SP-1, the largest of the five fragments obtained by cleavage at the four glutamoyl peptide bonds, was assigned to the amino terminus on the basis of composition, thereby representing residues 1-40. Cleavage of this peptide with trypsin yielded the peptide SP-1 (Tryp-l) corresponding in composition to the known sequence 1-16, and the larger peptide SP-1 (Tryp-2) evidently representing residues 17-40.

Commun. 44: 893-897. , and Lee, C. Y. (1970). The amino acid sequence of cardiotoxin from Formosan cobra (Naja naja afra) venom, Biochem. Biophys. Res. Commun. 41: 339-343. 14 Nobuyo Maeda et af. , and Hayashi, K. (1973). Localization of the five disulfide bridges in toxin B from the venom of the Indian cobra (Naja naja), Biochem. Biophys. Res. Commun. 55: 431438. Reisfeld, R. , Lewis, U. , and Williams, D. E. (1962). Disc electrophoresis of basic proteins and peptides on polyacrylamide gels, Nature (London) 195: 281-283.

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